Figures
Absorption spectra showing titration of G191 with Cl. The final spectrum is calculated using the Kd. The final spectrum is shown as a heavy line.
The Kd is approximately 0.5 M. Isosbestic points come at 418, 480, 524,and
604 nm. Maxima come at 410 nm (144.5 /mM.cm), 509 (11.8 /mM.cm),
and 634 nm (5.2 /mM.cm).
Canonical distal heme structure of a hydroxy complex. Note rotation of His 52 and Arg 48.
Proximal heme pocket of Q191 showing MES bound
MES binds in a similar fashion to both Q191 and Y191
Cl complex of the Y191 enzyme