Outline for Chapter 26 &
27: Nucleic Acids
1. Chromatin, chromosomes, gene
2. Composition of nucleic acids
3. Nucleotide, nucleoside, base
4. Structure of adenine, thymine, guanine, cytosine and uracil
5. Structure of nucleic acid chains (polymer)
6. Base-pairing in DNA, Watson-Crick Model, Major groove, Minor groove
7. Central dogma of molecular biology
8. DNA replication
9. Transcription
10. Translation
11. Structure of RNA
12. Types of RNA: ribosomal RNA, transfer RNA, messenger RNA
13. Introns and exons in RNA
14. RNA catalysis
15. Genetic disease and cancer
16. Recombinant DNA technology
17. Polymerase chain reaction (PCR)
18. Cloning
19. Human genome project, DNA sequencing
20. DNA fingerprinting
21. HIV and AIDS