Outline for Chapter 20:
Chemical Messengers
1. Hormones and Neurotransmitters
2. Endocrine system, control of hormone release
3. Types of hormones: (a) Polypeptide (b) Steroid (c) Amino acid derivatives
4. Interaction of hormones with receptors,
5. How hormones work: Epinepherine, role of second messenger cAMP
6. Steriod hormones, derivatives of sex hormone: ethynyl estradiol and norethindrone (birth control pills); Mifepristone (RU-486)
7. Nerve cell, transmission of nerve signal
8. Acetylcholine, Examples of agonists and antagonists that act at synapse
9. Histamine and Antihistamines
10. Monoamine: Serotonin, Norepinephrine, Dopamine
11. Drugs that affect the concentration of neurotransmitters at synapses: (a) Tricyclic antidepressants (Elavil) prevent the reuptake of srotonin and norepinephrine; (b) MAO inhibitors (Nardil) inhibit the enzyme that breaks down monoamine neurotransmitters; (c) SSRI antidepressants (Prozac) inhibit only the reuptake of serotonin.
11. Neuropeptides: Morphine, Enkephalin
12. Drug discovery: Benzocaine, Novocaine, Acetaminophen (Tylenol)