Outline for Chapter 19: Enzymes and Vitamins

Chapter 18

1.  Catalysis by enzymes

2. Substrate, active site, turnover number

3.  Enzyme co-factors

4.  Enzyme classification

5.  Mechanism of enzyme catalysis: (a) Lock and key model, (b) Induced-fit model

6.  Effect of temperature, pH, enzyme concentration and substrate concentration on activity

7.  Enzyme regulation: (a) Feedback control, (b) Allosteric control

8.  Enzyme inhibition: (a) Competitive, (b) Non-competitive, (c) Irreversible

9.  Covalent modification of enzymes: Zymogens/proenzyme, addition or removal of phosphoryl group

10.  Classification of vitamins: (a) Water-soluble, (b) Fat-soluble

11.  Role of vitamins in health

12. Antioxidants: Vitamin C and E; Selenium

13.  Enzymes in Medical Diagnosis

Chapter 20