Outline for Chapter 18: Amino
Acids and Proteins
1. Amino acids and protein structure: Primary, Secondary, Tertiary and Quaternary structure.
2. Peptide bond
3. Twenty common amino acids and their classification: Nonpolar, polar, acidic and basic.
4. Acid-base properties of amino acids, zwitterions, isoelectric point
5. Chirality, enantiomers, stereoisomers
6. Interactions reponsible for the shape of a protein molecule: Noncovalent interactions- (a) Hydrogen bonds (b) Ionic interactions (c) Hydrophobic interactions; Covalent interactions- Disulfide bonds between cysteine residues.
7. Types of secondary structure: alpha-helix and beta-sheet
8. Fibrous and Globular proteins, examples of each type of protein
9. Chemical properties of proteins: (a) Hydrolysis (b) Denaturation
10. Sickle-cell anemia